AstraZeneca said on Monday its vaccine for the novel coronavirus, developed along with the University of Oxford, could be around 90 per cent effective under one dosing regimen.
"This vaccine's efficacy and safety confirm that it will be highly effective against COVID-19 and will have an immediate impact on this public health emergency," Pascal Soriot, Astra's chief executive, said in a statement.
British Health Secretary Matt Hancock described as "fantastic news".
"These figures... show that the vaccine in the right dosage can be up to 90 per cent effective," he told Sky News, after an announcement from AstraZeneca.
"We've got 100 million doses on order and should all that go well, the bulk of the rollout will be in the new year."
The British drugmaker's preliminary trial results mark a fresh breakthrough in the fight against a pandemic that has killed nearly 1.4 million people and roiled the global economy.
The US military said on Saturday it carried out multiple strikes in Syria targeting ISIS as part of an operation that Washington launched in December after an attack on American personnel.
Israeli fire killed at least three Palestinians in two separate incidents across Gaza, local health authorities said, as tension rises over continued violence.
Tens of thousands of people marched through Minneapolis on Saturday to decry the fatal shooting of a woman by a US immigration agent, part of more than 1,000 rallies planned nationwide over the weekend against the federal government's deportation drive.
At least one person has died in Australia's southeast where bushfires raging for days have razed buildings, cut power to thousands of homes and burned swathes of bushland, police said on Sunday.