US President Donald Trump on Tuesday said he would remove all sanctions against Syria, saying they had served an important function, but it was now time for Syria to move forward.
"I will be ordering the cessation of sanctions against Syria in order to give them a chance at greatness," Trump told an investment forum in Riyadh.
"It's their time to shine. We're taking them all off," Trump said, "Good luck Syria, show us something very special," he added.
The United States imposed tough sanctions on Syria during the rule of Bashar al-Assad, and had kept them in place since he was toppled from power in December after more than 13 years of war.
Saudi Arabia has been a leading voice calling for the sanctions to be lifted.
Trump's latest announcement is a huge boost for interim Syrian President Ahmed al-Sharaa as he seeks to stabilise a country shattered by war.
Two sources from the Syrian presidency said Sharaa would travel to Riyadh to meet Trump.
The US military said on Saturday it carried out multiple strikes in Syria targeting ISIS as part of an operation that Washington launched in December after an attack on American personnel.
Israeli fire killed at least three Palestinians in two separate incidents across Gaza, local health authorities said, as tension rises over continued violence.
Tens of thousands of people marched through Minneapolis on Saturday to decry the fatal shooting of a woman by a US immigration agent, part of more than 1,000 rallies planned nationwide over the weekend against the federal government's deportation drive.
At least one person has died in Australia's southeast where bushfires raging for days have razed buildings, cut power to thousands of homes and burned swathes of bushland, police said on Sunday.