Britain's defending Olympic champion Andy Murray pulled out of the Tokyo 2020 men's singles tournament on Sunday ahead of his first-round match.
The 34-year-old, who had been due to play Canada's Felix Auger-Aliassime, was sidelined by a thigh strain.
Murray has been replaced in the draw by Australian Max Purcell.
The Scot will continue to compete in the men's doubles tournament with Joe Salisbury, Team GB said, the pair having won their opening match on Saturday.
"I am really disappointed at having to withdraw but the medical staff have advised me against playing in both events," a statement from Murray read.
"I have made the difficult decision to withdraw from the singles and focus on playing doubles with Joe."
Murray won Olympic gold on Wimbledon's Centre Court at the London 2012 Games, and defended his title in Rio.
He underwent hip surgery in 2018 and 2019, and missed the Australian Open at the start of this year after contracting COVID-19.
Abhishek Sharma's 19-ball fifty went in vain as world champions India were surprisingly beaten by Ireland for the first time in international cricket, slumping to a 34-run defeat in the first Twenty20 in Belfast on Friday.
England roared back into contention on the second day of the third and deciding test against New Zealand with Ben Duckett's rapid century helping his side to 223-2 after three wickets for returning captain Ben Stokes helped to dismiss the visitors for 438 at a sizzling Trent Bridge.
American great Serena Williams will face Australian 20-year-old Maya Joint in the first round of her eagerly awaited return to Wimbledon, a potentially tricky tie for the seven-time champion playing at the tournament for the first time since 2022.
Australia booked their spot in the knockout rounds of the World Cup on Thursday after a cagey draw against Paraguay, who are set to qualify as a third-placed finisher, while Turkey beat USA 3-2, scoring the winner with virtually the last kick of the match.