England beat Ireland and France by 12 and 36 points respectively in their first two matches of the campaign.
They are currently ranked third in the world.
Play from the Millennium Stadium in Cardiff gets underway at 8:45 PM UAE time.
Meanwhile Scotland travel to France for their latest Six Nations fixture.
Action from the Stade de France starts at 6:15 PM UAE time.
Rain in Montreal forces Canadian Open to reschedule men's quarter-finals
Rain has forced the cancellation of two Canadian Open men's quarter-finals scheduled for Monday in Montreal, tournament organisers said.
Swiatek cruises past Shnaider to reach Canadian Open semi-finals
Iga Swiatek has swept past Diana Shnaider 6-2 6-1 on Monday to reach the Canadian Open semi-finals, where the Pole will face Elina Svitolina after the Ukrainian rallied past Ekaterina Alexandrova in Toronto.
UEFA, AFC, CONCACAF hit out at Infantino over World Cup stake sale
European football's governing body UEFA, the Asian Football Confederation and CONCACAF issued an open letter on Monday attacking FIFA chief Gianni Infantino's conduct during the proposed sale of a stake in World Cup commercial rights.
Malawi book first-ever place at Women's World Cup
Malawi has continued its fairytale debut at the Women’s Africa Cup of Nations, coming from behind to beat Ghana 2-1 in Sunday’s last quarter-final, which also secured them a spot in the World Cup for the first time.
All Blacks lose Proctor to fractured shoulder on South Africa tour
New Zealand centre Billy Proctor will return home from his side's tour of South Africa after scans revealed a fractured shoulder sustained in the 38-21 victory over the Stormers in Cape Town on Friday.
