Serena Williams has missed out on winning a record-equalling 24th Grand Slam singles title on home soil this year.
She was beaten 1-6, 6-3, 6-3 in the semi-finals of the U.S. Open by Victoria Azarenka.
The unseeded Belarusian will play Japan's Naomi Osaka in the final on Saturday.
It will be Azarenka's third final at Flushing Meadows, having lost the previous two to Williams in 2012 and 2013.
Fourth seed Osaka had earlier beaten 28th seed Jennifer Brady 7-6, 3-6, 6-3 in the other semi-final.
Atletico beat 10-man Barca as PSG defeat Liverpool
Atletico Madrid took a firm grip on their Champions League quarter-final as goals from Julian Alvarez and Alexander Sorloth earned a 2-0 first-leg victory over 10-man Barcelona at the Camp Nou.
UAE Team Emirates-XRG claim second place on stage 3 of Itzulia Basque Country
Igor Arrieta has ridden to second place on stage 3 for UAE Team Emirates-XRG during a thrilling finale at Itzulia Basque Country,
Home hero Vacherot thrilled to beat Musetti in Monte Carlo
Monaco's Valentin Vacherot could barely have scripted his second career win over a top-five player better after he defeated world number five Lorenzo Musetti 7-6(6) 7-5 in front of a joyous home crowd at the Monte-Carlo Masters on Wednesday.
Gujarat survive IPL final-over chaos as Miller's gamble backfires
Gujarat Titans survived a ferocious late assault from David Miller to clinch a nerve-shredding one-run win over Delhi Capitals in an Indian Premier League (IPL) thriller on Wednesday.
Medvedev smashes racket during 6-0 6-0 loss in Monte Carlo
Daniil Medvedev smashed his racket several times during a humbling 6-0 6-0 loss to Italian wildcard Matteo Berrettini at the Monte Carlo Masters on Wednesday, as the world number 10 suffered his first tour‑level defeat without winning a game.
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