China ended a two-month lockdown in Wuhan, where the coronavirus was first detected, on Wednesday, but warned of a second-wave of infections.
Flights and trains have resumed operations, and highways opened to allow healthy residents and visitors to leave the capital of Hubei province.
Around 55,000 people are expected to leave the city, with authorities urging them not to leave unless absolutely necessary.
Wuhan, a city of 11 million people, was sealed off in late January to stop the spread of the virus. Over 50,000 people in Wuhan tested positive, while 2,500 died from the virus.
Meanwhile, new imported cases in the northern province of Heilongjiang continued to surge, forcing authorities to impose travel restrictions there.
The US military said on Saturday it carried out multiple strikes in Syria targeting ISIS as part of an operation that Washington launched in December after an attack on American personnel.
Israeli fire killed at least three Palestinians in two separate incidents across Gaza, local health authorities said, as tension rises over continued violence.
Tens of thousands of people marched through Minneapolis on Saturday to decry the fatal shooting of a woman by a US immigration agent, part of more than 1,000 rallies planned nationwide over the weekend against the federal government's deportation drive.
At least one person has died in Australia's southeast where bushfires raging for days have razed buildings, cut power to thousands of homes and burned swathes of bushland, police said on Sunday.